anti-mouse IFN gamma monoclonal antibody Anti-Mouse 100 µg

In stock

Cat-Nr.
103-M533
Size
100 µg
  €533.00

Description / anti-mouse IFN gamma monoclonal antibody

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.

More Information

Size 100 µg
Source Rat
Isotype IgG2
Clone Nr. (#7A13)
Formulation lyophilized
Buffer PBS
Reconstitution Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Preparation This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with recombinant mouse IFN-gamma, also known as type II or immune interferon).
Antigen Recombinant mouse IFN-gamma
Application WB, FC
Synonyms Ifng; Ifg; IFN-g
Uniprot ID P01580
Protein RefSeq NP_032363
mRNA RefSeq NM_008337

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