human IFN beta (Animal Free) protein Human 20 µg
Description / human IFN beta (Animal Free) protein
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues.
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Size | 20 µg |
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Source | E. coli |
Biological Activity | Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.25 ng/ml, corresponding to a specific activity of ≥ 4 x 106 units/mg. |
Purity Confirmation | ≥ 95% by SDS-PAGE gel and HPLC analyses. |
Length [aa] | 166 |
Molecular Weight | 20 kDa |
Species Reactivity | Human, Mouse |
Formulation | lyophilized |
Protein Sequence | MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN |
Synonyms | IFNB1; IFB; IFF; IFNB |
Uniprot ID | P01574 |
Protein RefSeq | NP_002167.1 |
mRNA RefSeq | NM_002176 |