human IFN beta (Animal Free) protein Human 20 µg

In stock

Cat-Nr.
100-191-AF
Size
20 µg
  €272.00

Description / human IFN beta (Animal Free) protein

Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections.  They also affect cell proliferation and modulate immune responses.  Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β.  Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens.  IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues. 

More Information

Size 20 µg
Source E. coli
Biological Activity Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.25 ng/ml, corresponding to a specific activity of ≥ 4 x 106 units/mg.
Purity Confirmation ≥ 95% by SDS-PAGE gel and HPLC analyses.
Length [aa] 166
Molecular Weight 20 kDa
Species Reactivity Human, Mouse
Formulation lyophilized
Protein Sequence MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
Synonyms IFNB1; IFB; IFF; IFNB
Uniprot ID P01574
Protein RefSeq NP_002167.1
mRNA RefSeq NM_002176

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