Description / GRO/MGSA
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant human GRO/MGSA is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human GRO/MGSA. Anti-human GRO/MGSA specific antibody was purified by affinity chromatography employing immobilized human GRO/MGSA matrix. Molecular weight is approx. 150 kDa. |
| Antigen | Recombinant human GRO/MGSA |
| Application | ELISA, WB, N, IHC |
| Synonyms | Growth Regulated Protein/Melanoma Growth Stimulatory Activity, MGSAα, NAP-3, GRO1, GRO, GROA, MGSA, SCYB1 |
| Uniprot ID | P03941 |
| Protein RefSeq | NP_001502.1Â |
| mRNA RefSeq | NM_001511.3 |