Description / GITR
GITR (glucocorticoid-induced tumor necrosis factor receptor), also named AITR (activation-inducible TNFreceptor superfamily member) and TNFRSF18, is a 228amino acid typeI transmembrane protein belonging to the TNFreceptor superfamily. The GITR cytoplasmic domain has striking similarity to the cytoplasmic domain of 4-1BB and CD27.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#7C13) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with Mouse T cells. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | mouse T cells |
| Application | IHC (P), FC |
| Synonyms | Tnfrsf18; AITR; Gitr |
| Uniprot ID | O35714 |
| Protein RefSeq | NP_033426.1 |
| mRNA RefSeq | NM_009400.2 |