Description / FGFR-3 neutralizing antibody
Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
More Information
| Size | 100 µg |
|---|---|
| Source | E. coli |
| Isotype | Fab-Fragment |
| Clone Nr. | Recombinant IG |
| Species Reactivity | human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C. |
| Synonyms | FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX |
| Uniprot ID | P22607 |
| Protein RefSeq | NP_000133 |
| mRNA RefSeq | NM_000142 |