Description / FGF-2 (basic)
FGF-basic or FGF-2 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
More Information
| Size | 200 µg |
|---|---|
| Source | Rabbit |
| Biological Activity | Western Blot: Use 2-5 µg/ml |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human FGF-2 (human Fibroblast Growth Factor-2, basic). Anti-human FGF-2 (basic) specific antibody was purified by affinity chromatography with immobilized Protein A. |
| Antigen | Recombinant human FGF-2 (basic) (RT #300-003) |
| Application | WB |
| Synonyms | FGF2; BFGF; FGFB; HBGF-2 |
| Uniprot ID | P09038 |
| Protein RefSeq | NP_001997.5 |
| mRNA RefSeq | NM_002006.4 |