Description / FGF-2 (basic)
FGF-Basic or FGF-2 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c x ICR F1 mice using highly pure recombinant human FGF-basic. Anti-Human FGF-basic-specific antibody was purified from cell culture by Protein G affinity chromatography. |
| Antigen | Recombinant Human FGF-basic (154 a.a.) |
| Application | ELISA, WB |
| Synonyms | FGF2; BFGF; FGFB; HBGF-2 |
| Uniprot ID | P09038 |
| Protein RefSeq | NP_001997.5 |
| mRNA RefSeq | NM_002006.4 |