Description / Fc gamma RIII
Receptors for the Fc region of IgG (Fc γ Rs) are members of the Ig superfamily that function in the activation or inhibition of immune responses such as degranulation, phagocytosis, ADCC (antibody-dependent cellular toxicity), cytokine release, and B cell proliferation. The Fc γ Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc γ RI (also known as CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#21Q2) |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Antigen | Recombinant mouse Fc gamma RIIb |
| Application | WB |
| Synonyms | Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII (FcRIII), CD16 |
| Uniprot ID | Q5D5J5 |
| Protein RefSeq | NP_001391947.1 |
| mRNA RefSeq | NM_001405018.1 |