Description / CTGFL
CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.8 kDa protein of 228 amino acid residues.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hCTGFL/WISP-2. Anti-hCTGFL/WISP-2 specific antibody was purified by affinity chromatography employing immobilized hCTGFL/WISP-2 matrix. |
| Antigen | Recombinant Human CTGFL/WISP-2 |
| Application | ELISA, WB |
| Synonyms | WISP2; CCN5; CT58; CTGF-L |
| Uniprot ID | O76076 |
| Protein RefSeq | NP_003872 |
| mRNA RefSeq | NM_003881 |