Description / CRIM1
CRIM1, also known as cysteine rich motor neuron 1, is a type I transmembrane glycoprotein containing an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 CRRs are similar to those in the BMP-binding antagonists such as Chordin. CRIM1 can interact with TGF-beta family ligands to modulate TGF-beta family ligand functions.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#16G1) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CRIM1 extracellular domain. |
| Antigen | Human recombinant CRIM1 EC domain |
| Application | WB |
| Synonyms | CRIM1; S52; CRIM-1 |
| Uniprot ID | Q9NZV1 |
| Protein RefSeq | NP_057525.1 |
| mRNA RefSeq | NM_016441.2 |