Description / Coagulation Factor X
Coagulation Factor X is a vitamin K-dependent plasma protease that activates thrombin in blood coagulation. Initially synthesized in the liver as a single-chain precursor, factor X is activated by both the intrinsic and extrinsic pathways to Xa, which consists of disulfide bond-linked light and heavy chains. The light chain contains a Gla and two EGF-like domains and the heavy chain corresponds to the serine protease domain.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#10A10) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Coagulation factor X. |
| Antigen | Human recombinant Coagulation factor X |
| Application | WB |
| Synonyms | F10; FX; FXA |
| Uniprot ID | P00742 |
| Protein RefSeq | NP_000495.1 |
| mRNA RefSeq | NM_000504.3 |