Description / Coagulation Factor III
Coagulation factor III is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as non-functional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#21U4) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Antigen | Recombinant human Coagulation Factor III (Tissue Factor) |
| Application | WB, IP, Capture Ab |
| Synonyms | Coagulation factor III, Thromboplastin, CD142 |
| Uniprot ID | P13726 |
| Protein RefSeq | NP_001171567.1 |
| mRNA RefSeq | NM_00118096.1 |