Description / CD83
CD83 is member of the Siglec family of transmembrane proteins. CD83 is a type I transmembrane glycoprotein that is a primary marker for dendritic cells. It also exists in multiple forms: membrane-bound CD83 is immunostimulatory while soluble CD83 is immunosuppressive. In the extracellular region, mouse and human CD83 are 66% identical at the aa level.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#4B34) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD83. |
| Antigen | human recombinant CD8 |
| Application | IHC, FC |
| Synonyms | CD83; BL11; HB15 |
| Uniprot ID | Q01151 |
| Protein RefSeq | NP_004224.1 |
| mRNA RefSeq | NM_004233.3 |