Description / CD31/PECAM-1, Antagonistic
The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions, on T cell subsets, and to a lesser extent, on platelets and most leukocytes. CD31 is required for the transendothelial migration of leukocytes through the intercellular spaces between vascular endothelial cells. This is a blocking antibody.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2a |
| Clone Nr. | (#2A14) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge the vial prior to opening. Reconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse endothelial membrane protein. |
| Antigen | Mouse endothelial membrane protein |
| Application | Inhibition |
| Synonyms | PECAM-1 |
| Uniprot ID | Q08481 |
| Protein RefSeq | NP_032842.2 |
| mRNA RefSeq | NM_008816.2 |