CD19

In stock

Cat-Nr.
101-M194
Size
100 µg
  €533.00

Description / CD19

B-lymphocyte antigen CD19 is a surface protein of the immunoglobulin superfamily. It binds to the B cell receptor on the cell surface of B cells and lowers the threshold of its activability. Thus, overexpression of CD19 in mice, as well as knockout mice, shows that CD19 affects the signaling threshold of receptors that regulate B lymphocyte selection, activation, and differentiation. At the molecular level, CD19 is involved in the activation of phosphatidylinositol 4,5-bisphosphate 3-kinases (PI3K). It is glycosylated and phosphorylated. Translated with www.DeepL.com/Translator (free version)

More Information

Size 100 µg
Source Mouse
Isotype IgG1
Clone Nr. (#13Q82)
Species Reactivity Human
Formulation lyophilized
Buffer PBS
Reconstitution Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Antigen Recombinant human CD19
Application FC
Synonyms B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12
Uniprot ID P15391
Protein RefSeq NP_001171569.1
mRNA RefSeq NM_001178098.1

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