CD163

In stock

Cat-Nr.
101-M291
Size
100 µg
  €533.00

Description / CD163

CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.

More Information

Size 100 µg
Source Mouse
Isotype IgG1
Clone Nr. (#6J58)
Species Reactivity Human
Formulation lyophilized
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD163 extracellular domain.
Antigen Human recombinant CD163 EC domain
Application WB, FC
Synonyms CD163; M130; MM130
Uniprot ID Q86VB7
Protein RefSeq NP_004235.4
mRNA RefSeq NM_004244

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