Description / C-10
Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recomb
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| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Mouse |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (98%) recombinant murine C-10. Anti-murine specific antibody was purified by affinity chromatography employing immobilized murine C-10 matrix. |
| Antigen | E.coli derived Recombinant Murine C10 (CCL6) |
| Application | ELISA, WB |
| Synonyms | Grcc10; PME; ULD; CST6; EPM1; STFB; EPM1A |
| Uniprot ID | O35127 |
| Protein RefSeq | NP_038563.1 |
| mRNA RefSeq | NM_013535.1 |