Human CD34, soluble
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| Cat-Nr. | S01-069S |
| Size | 5 µg |
| Price | 75 € |
| Source | E. coli |
| Label | His-Tag |
| Formulation | lyophilized |
| Purity Confirmation | > 95% by SDS-PAGE |
| Length [aa] | 267 |
| Molecular Weight | 28.6 kDa |
| N Terminal Sequence | SLDNN |
| Biological Activity | Data not available. |
| Species Reactivity | Human |
| Synonyms | CD34 |
| Description | CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein. |
| Protein Sequence | SLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLEHHHHHH |
| Uniprot ID | P28906 |
| Protein RefSeq | NP_001764.1 |
| mRNA RefSeq | NM_001773.2 |
Figures
SDS-PAGE analysis of recombinant human soluble CD34 produced in E. coli. Sample was loaded in 15% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.
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