Rat GRO/KC (CXCL1)
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| Cat-Nr. | R20-003 |
| Size | 25 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 72 |
| Molecular Weight | 7.8 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Rat, Mouse |
| Synonyms | Cxcl1; Gro1; CINC-1 |
| Description | All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
| Protein Sequence | APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK |
| Uniprot ID | P14095 |
| Protein RefSeq | NP_110472.1 |
| mRNA RefSeq | NM_030845.1 |
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