Mouse SDF-1 beta (CXCL12)
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| Cat-Nr. | M10-085S |
| Size | 2 µg |
| Price | 95 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 72 |
| Molecular Weight | 8.5 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml. |
| Species Reactivity | Human, Mouse |
| Synonyms | Pxorf31 |
| Description | SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1β is a 8.5 kDa protein containing 72 amino acid residues. |
| Protein Sequence | KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM |
| Uniprot ID | P40224 |
| Protein RefSeq | NP_068350.1 |
| mRNA RefSeq | NM_021704 |
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