Human Galectin-1
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| Cat-Nr. | 400-015 |
| Size | 50 µg |
| Price | 185 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & visualized by Coomassie stain |
| Length [aa] | 142 |
| Molecular Weight | 14,5 kDa |
| N Terminal Sequence | ACGLVASNLNLKPGE |
| Biological Activity | Testing in Progress. |
| Species Reactivity | Mouse, Human |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Human Galectin-1 should be reconstituted in water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C. |
| Stability and Storage | The lyophilized human Galectin-1, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human Galectin-1 should be stored in working aliquots at -20°C. |
| Synonyms | galectin-1; HBL; HPL; gal-1; HLBP14; galaptin; galectin 1; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14 kDa; GBP, GAL1; LGALS1 |
| Description | Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
| Protein Sequence | ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPF QPGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFDLEHHHH HH |
| Uniprot ID | P09382 |
| Protein RefSeq | NP_002296.1 |
| mRNA RefSeq | NM_002305.3 |
Figures
SDS-PAGE analysis of recombinant human Galectin-1. Sample was loaded in 15% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.
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