Human Apo-SAA1
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| Cat-Nr. | 100-387 |
| Size | 50 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 105 |
| Molecular Weight | ~11.7 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Human |
| Synonyms | Apo-SAA1 |
| Description | Recombinant human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA usually is 1-5 μg/ml in plasma. It increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. The human SAA gene codes for a 122 amino acid non-glycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. |
| Protein Sequence | MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY |
| Uniprot ID | P0DJI8 |
| Protein RefSeq | NP_000322.2 |
| mRNA RefSeq | NM_000331.4 |
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