Human MCP-4 (CCL13)
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Cat-Nr. | 100-068S |
Size | 5 µg |
Price | 95 € |
Source | E. coli |
Formulation | lyophilized |
Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
Length [aa] | 75 |
Molecular Weight | 8.6 kDa |
Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml. |
Species Reactivity | Monkey, Mouse, Human, Leech |
Synonyms | CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13 |
Description | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
Protein Sequence | QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT |
Uniprot ID | Q99616 |
Protein RefSeq | NP_005399 |
mRNA RefSeq | NM_005408 |
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