Human MCP-3 (CCL7)
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| Cat-Nr. | 100-067S |
| Size | 2 µg |
| Price | 95 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 76 |
| Molecular Weight | 9 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract BaF3 cells expressing human CCR2 receptor using a concentration range of 300-500 ng/ml. |
| Species Reactivity | Hasmter, Monkey, Mouse, Human |
| Synonyms | CCL7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7 |
| Description | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
| Protein Sequence | QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL |
| Uniprot ID | P80098 |
| Protein RefSeq | NP_006264 |
| mRNA RefSeq | NM_006273 |
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