Human GRO-gamma (CXCL3)
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| Cat-Nr. | 100-033 |
| Size | 10 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 73 |
| Molecular Weight | 7.9 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml. |
| Species Reactivity | Hamster, Human, Mouse |
| Synonyms | CXCL3; GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b |
| Description | All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant human GRO-γ is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
| Protein Sequence | ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN |
| Uniprot ID | P19876 |
| Protein RefSeq | NP_002081.2 |
| mRNA RefSeq | NM_002090.2 |
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