Human Exodus-2 (CCL21)
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| Cat-Nr. | 100-015 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 111 |
| Molecular Weight | 12.2 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Monkey, Mouse, Human, Leech, Pig |
| Synonyms | CCL21; ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21 |
| Description | Exodus-2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant human Exodus-2 is a 12.2 kDa protein containing 111 amino acid residues. |
| Protein Sequence | SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P |
| Uniprot ID | O00585 |
| Protein RefSeq | NP_002980 |
| mRNA RefSeq | NM_002989 |
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