Human EGF(Animal Free)
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Cat-Nr. | 100-008-AF |
Size | 100 µg |
Price | 135 € |
Source | E. coli |
Formulation | lyophilized |
Purity Confirmation | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
Length [aa] | 53 |
Molecular Weight | 6.2 kDa |
Endotoxin Levels | < 0.01 ng/ug of protein (< 0.1 EU/ug) |
Biological Activity | The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. |
Species Reactivity | Chicken, Cow, Dog, Hamster, Horse, Human, Human + Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Salamander, Snake, Tunicate, Zebra Fish |
Synonyms | Epidermal growth factor; EGF; URG; HOMG4; Urogastrone |
Description | EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Human EGF is a 6.2 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds. |
Protein Sequence | NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR |
Uniprot ID | P01133 |
Protein RefSeq | NP_001954.2 |
mRNA RefSeq | NM_1963.4 |
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