Human BD-2 (SAP1)
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| Cat-Nr. | 100-004 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 41 |
| Molecular Weight | 4.3 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract immature dendritic cells using a concentration of 10-100 ng/ml. |
| Species Reactivity | Human |
| Synonyms | DEFB4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102 |
| Description | Human ß-defensin-2 (BD-2) is an antimicrobial peptide which belongs to the distinct family of ß-defensins. Recent studies have shown that the ß-defensins are present in the human airways and may be relevant to the pathogenesis of cystic fibrosis lung disease. Human BD-2 is a 4.3 kDa protein containing 43 amino acid residues. |
| Protein Sequence | GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P |
| Uniprot ID | O15263 |
| Protein RefSeq | NP_004933.1 |
| mRNA RefSeq | NM_004942.2 |
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