Rabbit Anti-Human BMP-2
Slide this table
| Cat-Nr. | 102-PA106S |
| Size | 100 µg |
| Price | 170 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | human BMP-4 |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots. |
| Preparation | Anti-human BMP-2/4 polyclonal serum was produced from sera of rabbits pre- immunized with a highly purified synthetic peptide of the human BMP-2/4 sequence (C-terminal amino acids “C(SH)-L-D-E-Y-D-K-V-V-L-K-N-Y-Q-E-M-V-V-E-G“). Anti-human BMP-2/4 polyclonal antiserum was purified by Protein A chromatography. |
| Antigen | Recombinant human BMP-2 (RT# 200-002) |
| Application | WB, E |
| Synonyms | bone morphogenetic protein 2; BDA2; BMP2A; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 |
| Description | Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. The antibody cross-reacts displays cross-reaction with human BMP-4 monomers in Western Blot. |
| Uniprot ID | P12643 |
| Protein RefSeq | NP_001191 |
| mRNA RefSeq | NM_001200 |
Figures
Western Blot analysis of human BMP-2 with a polyclonal antibody directed against human BMP-2 derived from E. coli.
Reference
- An in vivo Comparison Study Between Strontium Nanoparticles and rhBMP2. G. Montagna et al., Front Bioeng Biotechnol. 2020; 8: 499.
All prices plus VAT + possible delivery charges