Rabbit Anti-Human FGF-7/KGF
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| Cat-Nr. | 102-P123 |
| Size | 100 µg |
| Price | 265 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human KGF (hKGF). Anti-human FGF-7 (KGF) specific antibody was purified by affinity chromatography employing immobilized human KGF matrix. |
| Antigen | Recombinant human KGF (FGF-7) |
| Application | ELISA, WB, N |
| Synonyms | KGF |
| Description | Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Human KGF/FGF-7 is an app. 19 kDa protein consisting of 163 amino acid residues. |
| Uniprot ID | P21781 |
| Protein RefSeq | NP_002000 |
| mRNA RefSeq | NM_002009 |
Reference
- A Bioengineering Approach for the Development of Fibroblast Growth Factor-7-Functionalized Sericin Biomaterial Applicable for the Cultivation of Keratinocytes. A. A. Lian et al., Int J Mol Sci. 2022 Sep; 23(17): 9953.
- Effects of transgenic silk materials that incorporate FGF‐7 protein microcrystals on the proliferation and differentiation of human keratinocytes. R. Maruta et al., FASEB Bioadv. 2020 Dec; 2(12): 734–744.
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