Mouse Anti-Human FGF-5
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| Cat-Nr. | 101-M71 |
| Size | 500 µg |
| Price | 275 € |
| Category | Monoclonal Antibody |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c mice using recombinant human FGF-5 as the immunizing antigen. This IgG1/K antibody was purified from a Protein A chromatography column. |
| Antigen | Recombinant human FGF-5 |
| Application | ELISA, N |
| Synonyms | FGF5; HBGF-5; Smag-82 |
| Description | The FGF family is comprised of at least seven polypeptides that are potent regulators of cell proliferation, differentiation and function. All FGFs have two conserved cysteine residues and share 30-50% sequence homology at the amino acid level. FGF5 was originally identified as a transforming gene by the NIH3T3 focus formation assay using DNA derived from human tumors. FGF5 cDNA encodes a 267 amino acid residue protein with a putative 22 amino acid residue signal peptide. The murine homologue of FGF5 was cloned and found to be 84% homologous to the human protein at the amino acid sequence level. Human and murine FGF5 exhibit cross species activity. In vitro, recombinant human FGF5 is a mitogen for Balb/3T3 fibroblasts and bovine heart endothelial cells. FGF5 was also reported to be a major muscle-derived survival factor for cultured spinal moto-neurons. |
| Uniprot ID | P12034 |
| Protein RefSeq | NP_004455 |
| mRNA RefSeq | NM_004464 |
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