Mouse Anti-Human NT-4
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Cat-Nr. | 101-M15 |
Size | 500 µg |
Price | 275 € |
Category | Monoclonal Antibody |
Isotype | IgG1 |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced in BALB/c x c57BL/6 F1 mice using recombinant human NT-4 as the immunizing antigen. IgG2a antibody was purified from ascites fluid on a Protein A affinity column. |
Antigen | Recombinant Human NT-4 |
Application | ELISA |
Synonyms | NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5 |
Description | NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues). |
Uniprot ID | P34130 |
Protein RefSeq | NP_006170.1 |
mRNA RefSeq | NM_006179.4 |
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